2022
Hyeri Nam, Younghwan Lee, Boil Kim, Ji-Won Lee, Seohyeon Hwang , Hyun-Kyu An, Kyung Min Chung, Youngjin Park, Jihyun Hong, Kyungjin Kim, Eun-Kyoung Kim, Han Kyoung Choe & Seong-Woon Yu. "Presenilin 2 N141I mutation induces hyperactive immune response through the epigenetic repression of REV-ERBα" Nature Communications, 13(1), 1-18. (2022)
2021
2020
2019
2018
2017
2016
Tae Seok Oh, Hanchae Cho, Jae Hyun Cho, Seong-Woon Yu, and Eun-Kyoung Kim. “Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression.” Autophagy, 12:2009-2025 (2016)
Jae Ryun Ryu, Caroline Jeeyeon Hong, Joo Yeon Kim, Eun-Kyoung Kim, Woong Sun*, and Seong-Woon Yu*. “Control of adult neurogenesis by programmed cell death in the mammalian brain.” Molecular Brain, 9:43 (2016)
Jaemeun Lee, Kyungchan Kim, Seong-Woon Yu, and Eun-Kyoung Kim. “Wnt3a upregulates brain-derived insulin by increasing NeuroD1 via Wnt/b-catenin signaling in the hypothalamus.” Molecular Brain, 9:24 (2016)
2015
Eun-Jung Kim, and Seong-Woon Yu*. “Translocator protein 18 kDa (TSPO): old dogma, new mice, new structure, and new questions for neuroprotection.” Neural Regeneration Research, 10:878-880 (2015)
Kyung Min Chung, Hyunhee Park, Seonghee Jung, Shinwon Ha, Seung Jun Yoo, Hanwoong Woo, Hyang Ju Lee, Seong Who Kim, Eun-Kyoung Kim, Cheil Moon, and Seong-Woon Yu*. “Calpain determines the propensity of adult hippocampal neural stem cells to autophagic cell death following insulin withdrawal.” Stem Cell, 33:3052-3064 (2015)
Jae Ho Cho, Jeong Hyang Park, Chang Geon Chung, Hyun-Jung Shim, Keun Hye Jeon, Seong-Woon Yu and Sung Bae Lee. “Parkin-mediated response against infection and wound involve TSPO-VDAC complex in Drosophila.” Biochemical and Biophysical Research Communications, 463:1-6 (2015)
Shinwon Ha, Hye Young Ryu, Kyung Min Chung, Seung-Hoon Baek, Eun-Kyoung Kim and Seong-Woon Yu*. “Regulation of autophagic cell death by glycogen synthase kinase-3b in adult hippocampal neural stem cells following insulin withdrawal.”Molecular Brain, 8:30 (2015)
Hyunjung Min, Jinpyo Hong, Ik-Hyun Cho, Yong Ho Yang, Hyunkyoung Lee, Dongwoon Kim, Seong-Woon Yu, Soojin Lee and Sung Joong Lee. “TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates collagenase-induced intracerebral hemorrhage.” Molecular Brain, 8:23 (2015)
2014
Heehong Hwang, Hyunjung Min, Donghoon Kim, Seong-Woon Yu, Sung Jun Jung, Se-Young Choi and Sung Joong Lee. “Imiquimod induces a Toll-like receptor 7-independent increase in intracellular calcium via IP3receptor activation.” Biochem. Biophys. Res. Commun., 450:875-879 (2014)
Hyojin Cho, Hyun-Jung Shim and Seong-Woon Yu*. “Attenuation of Translocator protein 18 kDa (TSPO) up-regulation by peroxisome proliferator-activated receptor g ligand in activated microglia.” Quantitative Bio-Science, 33:41-45 (2014)
Seung-Hoon Baek, Ah Reum Noh, Kyeong-A Kim, Muhammad Akram, Young-Jun Shin, Eun-Sun Kim, Seong-Woon Yu, Ok-Nam Bae and Arshad Majid. “Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage.” Stroke, 45:2438-2443 (2014)
Keun-Lyung Bae, Hyun-Jung Shim, Deebika Balu, Sang-Ryong Kim and Seong-Woon Yu*. “Translocator Protein 18 kDa (TSPO) Negatively Regulates Inflammation in Activated Microglia.” J. Neuroimmune Pharmacology, 9:424-437 (2014)
2013
Kyoung Min Chung and Seong-Woon Yu*. “Interplay between autophagy and programmed cell death in mammalian neural stem cells.” BMB Reports, 46:383-390 (2013)
Seung-Hoon Baek, Ok-Nam Bae, Eun-Kyoung Kim and Seong-Woon Yu*. “Induction of mitochondrial dysfunction by poly(ADP-ribose) polymer: implication for neuronal cell death.” Mol. Cells, 36:258-266, (2013)
2012
Seung-Hoon Baek, Ok-Nam Bae and Seong-Woon Yu*. “Mitochondrial Bioenergetics of Brain Mitochondria Isolated from Parkin Null Mice.” Quantitative Bio-Science, 31:133-137 (2012)
2011
Geun-Lyung Bae, Sang-Ryong Kim, Seong-Woon Yu*. “The Inhibitory Effects of Peripheral Benzodiazepine Receptor Ligands on Microglia Activation.” Quantitative Bio-Science,30:101-105 (2011)
Jiangyong Min, Seong-Woon Yu, Seung-Hoon Baek, Kavitha M. Nair, Ok-Nam Bae, Archit Bhatt, Mounzer Kassab, Muraleedharan G. Nair, Arshad Majid. “Neuroprotective effect of cyaniding-3-O-glucoside anthocyanin in mice with focal cerebral ischemia.” Neuroscience Letters, 500:157-161 (2011)
2010
Hwanju Cheon, jae Min Cho, Sunshin Kim, Seung-Hoon Baek, Moon-Kyu Lee, Kwang-Won Kim, Seong-Woon Yu, Giovanni Solinas, Soung Soo Kim and Myung-Shik Lee. “Role of JNK activation in pancreatic b-cell death by streptozotocin.” Mol. Cell. Endocrinol.,321:131-137 (2010)
Diana Han, Byungho Yang, L. Karl Olson, Alexander Greenstein, Seung-Hoon Baek, Kate J. Claycombe, John L. Goudreau, Seong-Woon Yu, and Eun-Kyoung Kim. “Activation of autophagy through modulation of AMP-activated protein kinase protects pancreatic beta cells from high glucose.” Biochemical J., 425:541-551 (2010)
2009
Seong-Woon Yu, Yingfei Wang, Didrik S. Frydenlund, Ole Petter Ottersen, Valina L. Dawson and Ted M. Dawson. “Outer Mitochondrial Membrane Localization of Apoptosis-Inducing Factor: Mechanistic Implications for Release.” ASN Neuro., 1:275-281 (2009)
Seung-Hoon Bake, Eun-Kyoung Kim, Hyangju Lee, Se Kyong Park, Keith J. Lookingland, John L. Goodreau, Seong Who Kim and Seong-Woon Yu*. “Autophagic Cell Death in Adult Neural Stem Cells.” Cell Transplantation, 18:209 (2009)
Rajanikant Krishnamurthy, Marie-Claude Senut, Daniel Zemke, John Min, Mark B. Frenkel, Eric J. Greenberg, Seong-Woon Yu, Nicholas Cho Ahn, John Goudreau and Arshad Majid. “Asiatic Acid, a Pentacyclic Triterpene from Centella asiatica is Neuroprotective in a Mouse Model of Focal Cerebral Ischemia.” J. Neurosci. Resear., 87:2541-2150 (2009)
Seung-Hoon Baek, Eun-Kyoung Kim, John L. Goudreau, Keith J. Lookingland, Seong Who Kim and Seong-Woon Yu*. “Insulin withdrawal-induced cell death in adult hippocampal neural stem cells as a model of autophagic cell death.” Autophagy,5:277-279 (2009)
[ Invited article ]
2008
Seong-Woon Yu*, Seung-Hoon Baek, Ryan T. Brennan, Christopher J. Bradley, Se Kyung Park, Yoon Sun Lee, Eun Jung Jun, Keith J. Lookingland, Eun-Kyoung Kim, Heuiran Lee, John L. Goudreau and Seong Who Kim. “Autophagic Death of Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal.” Stem Cells, 26:2602-2610 (2008)
Selected for Faculty of 1000 Medicine (URL=http://www.f1000medicine.com/article/qtfznstb1bj7jyr/id/1158051)
2007
2006
Saskia Biskup, Darren Moore, Fulvio Celsi, Shinji Higashi, Andrew West, Shaida A. Andrabi, Kaisa Kurkinnen, Seong-Woon Yu, Joe M. Savitt, Henry J. Waldvogel, Richard L.M. Faull, Piers C. Emson, Reidun Torp, Ole P. Ottersen, Ted M. Dawson and Valina L. Dawson. “Localization of LRRK2 to Membranous and Vesicular Structures in Mammalian Brain.” Annal. Neurology, 60:557-569 (2006)
Seong-Woon Yu, Shaida A. Andrabi, No Soo Kim, Hongmin Wang, Guy G. Poirier, Ted M. Dawson and Valina L. Dawson. “Apoptosis Inducing Factor Mediates Poly (ADP-ribose) (PAR) Polymer Induced Cell Death”. Proc. Natl. Acad. Sci. U.S.A., 103:18314-18319 (2006)
Shaida A. Andrabi, No Soo Kim, Seong-Woon Yu, Hongmin Wang, David W. Koh, Masayuki Sasaki, Judith A. Klaus, Takatshi Otsuka, Zhizheng Zhang, Raymond C. Koehler, Patricia D. Hurn, Guy G. Poirier, Valina L. Dawson, and Ted M. Dawson. “Poly (ADP-Ribose) (PAR) Polymer is a Death Signal.” Proc. Natl. Acad. Sci. U.S.A., 103:18308-18313 (2006)
2005
Xiaoling Li, Masaaki Nemoto, Seong-Woon Yu, Ted M. Dawson, Valina L. Dawson, Raymond C. Koehler. “Early Reperfusion after Focal Cerebral Ischemia Accelerates Translocation of Apoptosis-Inducing Factor to the Nucleus.” Stroke, 36:510 (2005)
2004
2003
2002
Seong-Woon Yu, Hongmin Wang, Marc F. Poitras, Carmen Coombs, William J. Bowers, Howard J. Federoff, Guy G. Poirier, Ted M. Dawson and Valina L. Dawson. “Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.” Science,297:259-263 (2002)
[ Selected as a hot paper by Thompson Reuter Research group in November 2003, selected as a hot paper by The Scientist in February 2005. Cited 1,795 by Google Scholar. ]
1999
1996
Patent
1. Pharmaceutical compositions for the prevention and treatment of the neurodegenerative disorders. (No. 10-1600666), 2016, Republic of Korea
2. Method for determination of metabolites changed by Translocator protein 18 kDa in hypothalamus cells. (No. 10-1796891), 2017, Republic of Korea
3. Ascorbate oxidase (No. 184126), 1998